Product Name :
SPARC Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
AA517111 antibody Basement membrane protein 40 antibody Basement-membrane protein 40 antibody BM 40 antibody BM-40 antibody BM40 antibody Cysteine rich protein antibody hm:zeh0062 antibody MGC128090 antibody OI17 antibody 展开
Function :
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human SPARC 101-200/303
Species reactivity:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Verify application:
WB, ELISA, IHC-P, FC, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.Price of Methyltetrazine-Amine When reconstituted in sterile pH 7.Buy1-Benzyl-1H-1,2,4-triazole 4 0.PMID:33615903 01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
33 KDa
Positive control :
Mouse Brain Lysate, human lung carcinoma tissue, Human Meningioma tissue, Human colon cancer tissue, A549 Cell Lysate, human brain glioma tissue, mouse brain tissue, Rat brain tissue.