Product Name :
S100A10 Recombinant Rabbit Monoclonal Antibody [JF0987]
Predicted band size :
11 kDa
Observed band size :
11 kDa
Synonyms:
42C antibody AA409961 antibody AL024248 antibody Annexin II ligand antibody Annexin II ligand, calpactin I, light polypeptide antibody Annexin II tetramer (AIIt) p11 subunit antibody Annexin II, light chain antibody ANX2L antibody ANX2LG antibody Ca[1] antibody 展开
Function :
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human S100A10 aa 19-68 / 97.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Tissue
Coupling :
unconjugated
Clone number:
JF0987
RRID:
AB_3070300
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃.1-(Difluoromethyl)-4-iodo-1H-pyrazole Chemscene Avoid repeated freeze / thaw cycles.9-Aminononan-1-ol web
Storage buffer solution:
1*TBS (pH7.PMID:33472818 4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 11 kDa
Positive control :
A549 cell lysate, human lung tissue lysates, human lung tissue, human colon cancer tissue, human colon tissue, mouse colon tissue, rat colon tissue.