Product Name :
PLCG 2 Recombinant Rabbit Monoclonal Antibody [JE39-12]
Predicted band size :
148 kDa
Observed band size :
148 kDa
Synonyms:
1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody 1-phosphatidylinositol-4 antibody 5-bisphosphate phosphodiesterase gamma-2 antibody EC 3.1.4.11 antibody Phosphoinositide phospholipase C antibody Phosphoinositide phospholipase C-gamma-2 antibody Phospholipase C gamma 2 antibody Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody Phospholipase C-gamma-2 antibody Phospholipase C-IV antibody 展开
Function :
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C-beta is regulated by heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1; MIM 172420) and C-gamma-2 enzymes are controlled by receptor tyrosine kinases. The C-gamma-1 and C-gamma-2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PLCG 2 aa 721-770 / 1,265.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
JE39-12
RRID:
AB_3072593
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of 73286-71-2 Aliquot store at -20℃.1300746-79-5 Price Avoid repeated freeze / thaw cycles.PMID:33694125
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 148 kDa
Positive control :
Raji cell lysate, Daudi cell lysate, human lymph nodes tissue, mouse kidney tissue, rat kidney tissue, Raji, Daudi.