Product Name :
SLP-76 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
76 kDa tyrosine phosphoprotein antibody CG8697 antibody LCP 2 antibody LCP2 antibody LCP2_HUMAN antibody Lymphocyte cytosolic protein 2 antibody SH2 domain containing leukocyte protein 76 KD antibody SH2 domain containing leukocyte protein of 76kD antibody SH2 domain containing leukocyte protein of 76kDa antibody SH2 domain-containing leukocyte protein of 76 kDa antibody 展开
Function :
SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from SLP-76 . at AA range: 270-350
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1376340-66-7 Data Sheet Aliquot store at -20℃ or -80℃.2166539-35-9 uses Avoid repeated freeze / thaw cycles.PMID:33682528
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
60 kDa
Positive control :
Leukemia,Platelet,Prostate,T-cell,